Mokola Virus in Domestic Mammals, South Africa
نویسندگان
چکیده
We recently identified 2 Mokola viruses from domestic mammals (a dog and a cat) in South Africa. These cases occurred 8 years after the last reported case of infection with this virus. Our findings emphasize the endemicity of rabies-related lyssaviruses in South Africa and the need to better understand the epidemiology of Mokola viruses.
منابع مشابه
New isolations of the rabies-related Mokola virus from South Africa
BACKGROUND Mokola virus (MOKV) is a rabies-related lyssavirus and appears to be exclusive to the African continent. Only 24 cases of MOKV, which includes two human cases, have been reported since its identification in 1968. MOKV has an unknown reservoir host and current commercial vaccines do not confer protection against MOKV. RESULTS We describe three new isolations of MOKV from domestic ca...
متن کاملMokola virus infection: description of recent South African cases and a review of the virus epidemiology.
Five cases of Mokola virus, a lyssavirus related to rabies, are described. The cases occurred in cats from the East London, Pinetown and Pietermaritzburg areas of South Africa from February 1996 to February 1998. Each of the cats was suspected of being rabid and their brains were submitted for laboratory confirmation. Four of the cases were positive, but with atypical fluorescence, and 1 was ne...
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This report, covering the two year period 1997 to 1998, is an update of previous reports published in the Proceedings of SEARG meetings which took place in Zambia, South Africa, Zimbabwe and Kenya. The overall rabies situation in South Africa has changed very little and the disease remains endemic throughout the country. Four major vectors have been identified, namely the domestic dog, the yell...
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There are at least six Lyssavirus species that have been isolated in Africa, which include classical rabies virus, Lagos bat virus, Mokola virus, Duvenhage virus, Shimoni bat virus and Ikoma lyssavirus. In this retrospective study, an analysis of the antigenic reactivity patterns of lyssaviruses in South Africa against a panel of 15 anti-nucleoprotein monoclonal antibodies was undertaken. A tot...
متن کاملDiversity and Epidemiology of Mokola Virus
Mokola virus (MOKV) appears to be exclusive to Africa. Although the first isolates were from Nigeria and other Congo basin countries, all reports over the past 20 years have been from southern Africa. Previous phylogenetic studies analyzed few isolates or used partial gene sequence for analysis since limited sequence information is available for MOKV and the isolates were distributed among vari...
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عنوان ژورنال:
دوره 13 شماره
صفحات -
تاریخ انتشار 2007